DNA double-strand break – induced pro-survival signaling
نویسندگان
چکیده
منابع مشابه
DNA double-strand break repair
The integrity of genomic DNA is crucial for its function. And yet, DNA in living cells is inherently unstable. It is subject to mechanical stress and to many types of chemical modification that may lead to breaks in one or both strands of the double helix. Within the cell, reactive oxygen species generated by normal respiratory metabolism can cause double-strand breaks, as can stalled DNA repli...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2011
ISSN: 0167-8140
DOI: 10.1016/j.radonc.2011.05.074